Collagen & Skin Boosters · Seomyeon, Busan
Rejuran HB in Busan
#PNPlusHA · #RepairAndHydrate · #DewyVitality · #TiredSkinCare
Rejuran HB is a skin booster that combines PN with hyaluronic acid. It supports repair and hydration together, bringing dewy vitality and elasticity back to dry, tired skin.
Quick answer: Rejuran HB is a skin booster that combines PN (polynucleotide) with hyaluronic acid to support skin repair and hydration at the same time. At Art of Shine Clinic in Seomyeon, Busan, it takes about 10–20 minutes after numbing cream, with mild swelling or needle marks for 1–2 days. A series of 3 or more sessions 2–4 weeks apart is usually advised. Rejuran HB 2cc is listed at KRW 390,000 (excl. 10% VAT).
At a glance
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✔ Medically reviewed byDr. Park Yoon-soo, Head Director, Art of Shine Clinic · Last reviewed:


What is Rejuran HB?
Rejuran HB is part of the Rejuran range by PharmaResearch, a Korean company. Like the original Rejuran, it contains PN (polynucleotide) derived from salmon DNA, which supports the skin's natural repair processes. The HB version adds hyaluronic acid for extra hydration.
It suits skin that is both dry and tired-looking, with fine lines or loss of bounce. If repair is your main concern, Rejuran Healer is the classic choice; for hydration alone, Re2O or Belotero Revive may be enough.
How Rejuran HB works
PN provides building blocks that support cell repair and a healthier skin environment, while hyaluronic acid draws moisture into the skin. Together they improve hydration, elasticity and overall skin condition over a series of sessions.
- Consultation: your doctor assesses dryness, fine lines and skin condition, and checks for fish allergies.
- Treatment: after numbing cream, Rejuran HB is injected in small, even points across the face.
- After: you can return to daily life; repeat sessions every 2–4 weeks build the result.
Why patients choose Rejuran HB
- PN plus hyaluronic acid — repair and hydration in one treatment.
- From an established range — part of PharmaResearch's Rejuran line.
- Dewy, healthier skin — aimed at dry, tired-looking complexions.
- Short appointment — about 10–20 minutes after numbing cream.
Who is Rejuran HB for — and when we suggest something else
Good candidates
- Your skin is both dry and tired-looking, with a dull, stressed surface.
- Fine lines show more when your skin is dehydrated.
- You want repair and hydration from one booster.
- You have tried a hydration booster before and want more resilience.
- You can plan three or more sessions 2–4 weeks apart.
We may suggest something else if…
- Repair and elasticity matter more than hydration — classic Rejuran Healer may be enough.
- You only want hydration and glow — Re2O is a simpler option.
- Texture, pores or scars are the priority — Juvelook Skin targets collagen there.
- You are allergic to fish or salmon-derived products. Tell us first; Dr. Park will suggest a non-PN alternative.
- You are pregnant or breastfeeding, or have an active skin infection. We will wait.
What happens at your Rejuran HB session in Seomyeon
- Message us on WhatsApp first. Send us on WhatsApp (+82 10-2689-0370) a daylight photo and your dates. Mention any fish allergy or previous reaction to boosters.
- Consultation with Dr. Park. She checks dryness, fine lines, skin thickness and sensitivity. She confirms whether HB or classic Rejuran Healer suits you better.
- Preparation and numbing. Your skin is cleansed and numbing cream is applied for about 20–30 minutes.
- The treatment. Injecting takes about 10–20 minutes. Expect pricking and small blebs; PN boosters can sting a little.
- Out the door and follow-up. Mild swelling or needle marks may last 1–2 days. Your next session is usually 2–4 weeks later.
How Dr. Park plans your Rejuran HB treatment
Dr. Park places Rejuran HB in small, shallow deposits across the face. Areas that look dry and creased, such as the cheeks and under-eye margin, often get closer spacing.
Our listed package is Rejuran HB 2cc. That amount is planned across the zones that need it most. Sessions are spaced 2–4 weeks apart, and three or more are usually advised.
She aims for dewy, resilient skin rather than visible change in shape. Dr. Park is a REJURAN & REJUVIEL Expert Member (PharmaResearch), the company behind Rejuran.
Rejuran HB results: what to expect and when
- First days: small bumps and needle marks settle within 1–2 days.
- Weeks 1–3: skin feels more hydrated and looks fresher.
- After 3 sessions: elasticity and overall condition improve most.
- Ongoing: how long results last varies by person; plan maintenance with your doctor.
Results vary by person.
Side effects, risks and who should avoid Rejuran HB
Rejuran HB is generally well tolerated when performed by a doctor. Possible side effects include:
- Small bumps or visible injection marks for 1–2 days
- Redness, mild swelling or tenderness
- Bruising at some injection points, which fades over several days
- Rarely, infection, allergic reaction or persistent lumps — contact the clinic if anything worsens
Not suitable if you: are pregnant or breastfeeding; are allergic to fish or salmon-derived ingredients; have an active skin infection, cold sore or inflamed acne in the area; have an uncontrolled autoimmune condition; or tend to form keloid scars. Tell your doctor about all medications, especially blood thinners.
Rejuran HB vs Rejuran Healer and Re2O: which should you choose?
Rejuran HB sits between a PN repair booster and a hydration booster.
| Treatment | How it works | Best for | Downtime | Results last |
|---|---|---|---|---|
| Rejuran HB | PN combined with hyaluronic acid | Dry, tired skin needing repair and moisture | Mild swelling or needle marks for 1–2 days | Varies; 3+ sessions advised |
| Rejuran Healer | Salmon-derived PN | Repair, elasticity, texture | Mild swelling or needle marks for 1–2 days | Varies; 3+ sessions advised |
| Re2O | Hyaluronic acid only | Hydration and glow | Mild swelling or needle marks for 1–2 days | Varies; 3+ sessions advised |
Choose Rejuran HB if your skin is both dry and tired. Choose Rejuran Healer if repair is the main need, and Re2O if you only need hydration.
Aftercare after Rejuran HB
- For about 3–4 hours, avoid lying face-down and do not rub the treated area.
- On the day of treatment, skip saunas, hot baths, strenuous exercise and alcohol.
- Do not massage or press firmly on the treated area.
- Temporary swelling, bruising or tenderness can occur and usually settles on its own.
- Results and how long they last vary with your skin condition and lifestyle.
Travelling? Read our aftercare tips for travellers.
Downtime after Rejuran HB, and flying home
Small bumps usually flatten within hours to a day, and needle marks fade in 1–2 days. Do not lie down or rub your face for 3–4 hours. Skip saunas, hot baths, alcohol and hard workouts that day. Avoid massage or pressure on the area.
A gentle afternoon in Seomyeon or a seaside walk is usually fine. Leave jjimjilbang visits for later in the trip. Most people resume make-up the next day. Keep skin moisturised on the flight home. Share your flight date with Dr. Park at consultation. See our aftercare tips for travellers.
Rejuran HB prices in Busan (KRW)
| Package | Regular | Price |
|---|---|---|
| Rejuran HB 2cc AOS Skin Booster Package |
KRW 390,000 40% off |
Listed amounts are non-covered treatment fees in Korean won (KRW) and exclude 10% VAT. Payment is made at the clinic on the day of your visit. Costs may vary with the treatment area and dosage, and results, recovery time and side effects differ from person to person. Details are explained during an in-clinic consultation. Event prices and periods change — please confirm on WhatsApp when you book. Prices checked: October 2026.
Full price list → · Current special offers → · How prices & payment work →
What does HB mean in Rejuran HB?
Rejuran HB is a version of Rejuran that adds hyaluronic acid to the PN base. In practice, it is chosen when hydration is needed alongside repair. The core ingredient, salmon-derived PN, is the same family as Rejuran Healer. The added hyaluronic acid gives a more moisturising effect. Product names and formulations can change between markets. If you want the exact ingredient list, ask Dr. Park to show you the product label at your visit. She can also explain why she chose HB rather than Healer for your skin.
Is Rejuran HB less painful than Rejuran Healer?
Many people find PN boosters sting a little, and comfort varies widely. Numbing cream is applied for about 20–30 minutes first in every case. Some patients report Rejuran HB feels more comfortable, but this is individual. Pain also depends on the area treated, your skin thickness and your stress level that day. Tell the team if you are sensitive; you can ask for a break at any time. Choose the product for your skin's needs, not comfort alone.
Can I have Rejuran HB if I'm allergic to fish?
Tell us before booking. Rejuran products contain PN derived from salmon. A fish allergy does not always mean a reaction, but caution is sensible. Dr. Park will ask about your allergy history and how severe past reactions were. If there is real doubt, she will suggest a booster without PN, such as Re2O or Juvelook Skin. Never hide an allergy to get a specific treatment; your safety comes first. Bring any allergy documents you have, translated if possible, to your consultation.
Rejuran HB FAQ
How much does Rejuran HB cost in Busan?
At Art of Shine Clinic in Seomyeon, Rejuran HB 2cc is KRW 390,000 in our skin booster package, reduced from KRW 650,000 (excl. 10% VAT). Prices change with events, so please confirm on WhatsApp when you book.
Does Rejuran HB hurt?
Numbing cream is applied for about 20–30 minutes first, so most people feel only light pricking and mild pressure. Sensitivity varies by area and person, and you can ask for a break at any time. Tell us if you are sensitive to pain.
How many Rejuran HB sessions do I need?
Most people are advised to have 3 or more sessions about 2–4 weeks apart. Skin repair and hydration build gradually, and how long results last depends on your age, skin condition and lifestyle.
Can I go sightseeing or fly after Rejuran HB?
Yes. Small bumps, redness or needle marks can last 1–2 days, but most people carry on with their day and can fly. Avoid saunas, hot baths, alcohol and hard exercise on the day, and tell your doctor about your travel dates.
What is the difference between Rejuran HB and Rejuran Healer?
Both contain salmon-derived PN to support skin repair. Rejuran HB adds hyaluronic acid for extra hydration, so it suits dry, tired skin. Rejuran Healer focuses on repair, elasticity and texture. Your doctor will suggest the right fit for your skin.
Who performs Rejuran HB at your clinic?
Dr. Park Yoon-soo, our Head Director, plans and performs your treatment. She is a REJURAN & REJUVIEL Expert Member (PharmaResearch) and trained at Kyungpook National University School of Medicine and Asan Medical Center.
Can I book Rejuran HB on short notice?
Often, depending on the schedule. We are open Mon–Fri 10:00–20:00 and Sat 10:00–16:00, closed for lunch 13:00–14:00 and on Sundays. Message us on WhatsApp to check a slot.
How do I pay for Rejuran HB?
Payment is made at the clinic on the day of your visit. Listed prices are in Korean won and exclude 10% VAT. Ask on WhatsApp if you have questions about payment before you travel.
Related treatments
- Rejuran Healer — PN booster for skin repair
- Re2O — hyaluronic acid hydration booster
- Belotero Revive — hydration and fine-line care
- CellREDM — booster for firmer, healthier skin
- Exosome — calming care for stressed skin
- Juvelook Skin — PDLLA booster for texture and pores
See all Collagen & Skin Boosters or browse all 98 treatments.
Medically reviewed by
Dr. Park Yoon-soo— Head Director, Art of Shine Clinic Busan
Medical graduate of Kyungpook National University School of Medicine, intern at Asan Medical Center. Rejuran and Rejuviel Expert Member (PharmaResearch), Restylane Expert Member (Galderma), Belotero Key Doctor (Merz Korea) and 2026 Coretox Expert. Member of the Korean Aesthetic Surgery & Laser Society and the Korean Society for Laser, Dermatology and Trichology.
This page is for general information and does not replace an in-person medical consultation. Results, recovery time and side effects vary from person to person.
Ready to plan your visit?
Send one WhatsApp message with the treatment and your travel dates. We reply during clinic hours (KST): Mon–Fri 10:00–20:00, Sat 10:00–16:00.








